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AX-024 HCl

CAS No. 1704801-24-0

AX-024 HCl ( —— )

Catalog No. M17365 CAS No. 1704801-24-0

AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 68 In Stock
5MG 105 In Stock
10MG 161 In Stock
25MG 375 In Stock
50MG 557 In Stock
100MG 791 In Stock
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Biological Information

  • Product Name
    AX-024 HCl
  • Note
    Research use only, not for human use.
  • Brief Description
    AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
  • Description
    AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    IL-6; TNFα; IFN-γ; IL-10; IL-17A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1704801-24-0
  • Formula Weight
    375.87
  • Molecular Formula
    C21H23ClFNO2
  • Purity
    98%
  • Solubility
    DMSO : 33 mg/mL 87.80 mM; H2O : 16.67 mg/mL. 44.35 mM;
  • SMILES
    Cl.Fc1ccc(cc1)C=3c4cc(ccc4OCC=3CN2CCCC2)OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Borroto A, etal. First-in-class inhibitor of the T cell receptor for the treatment of autoimmune diseases. Sci Transl Med. 2016 Dec 21;8(370):370ra184.
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