AX-024 HCl ( —— )

Catalog No. M17365 CAS No. 1704801-24-0

AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.

Purity : 98%

COA

Datasheet

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Size	Price / USD	Stock	Quantity
2MG	68	In Stock
5MG	105	In Stock
10MG	161	In Stock
25MG	375	In Stock
50MG	557	In Stock
100MG	791	In Stock
200MG	Get Quote	In Stock
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Biological Information

Product Name

AX-024 HCl
Note

Research use only, not for human use.
Brief Description

AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
Description

AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

IL-6; TNFα; IFN-γ; IL-10; IL-17A
Research Area

——
Indication

——

Chemical Information

CAS Number

1704801-24-0
Formula Weight

375.87
Molecular Formula

C21H23ClFNO2
Purity

98%
Solubility

DMSO : 33 mg/mL 87.80 mM; H2O : 16.67 mg/mL. 44.35 mM;
SMILES

Cl.Fc1ccc(cc1)C=3c4cc(ccc4OCC=3CN2CCCC2)OC
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Borroto A, etal. First-in-class inhibitor of the T cell receptor for the treatment of autoimmune diseases. Sci Transl Med. 2016 Dec 21;8(370):370ra184.

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